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DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia.
Hannon, Eilis; Dempster, Emma L; Mansell, Georgina; Burrage, Joe; Bass, Nick; Bohlken, Marc M; Corvin, Aiden; Curtis, Charles J; Dempster, David; Di Forti, Marta; Dinan, Timothy G; Donohoe, Gary; Gaughran, Fiona; Gill, Michael; Gillespie, Amy; Gunasinghe, Cerisse; Hulshoff, Hilleke E; Hultman, Christina M; Johansson, Viktoria; Kahn, René S; Kaprio, Jaakko; Kenis, Gunter; Kowalec, Kaarina; MacCabe, James; McDonald, Colm; McQuillin, Andrew; Morris, Derek W; Murphy, Kieran C; Mustard, Colette J; Nenadic, Igor; O'Donovan, Michael C; Quattrone, Diego; Richards, Alexander L; Rutten, Bart Pf; St Clair, David; Therman, Sebastian; Toulopoulou, Timothea; Van Os, Jim; Waddington, John L; Sullivan, Patrick; Vassos, Evangelos; Breen, Gerome; Collier, David Andrew; Murray, Robin M; Schalkwyk, Leonard S; Mill, Jonathan.
Afiliação
  • Hannon E; University of Exeter Medical School, University of Exeter, Barrack Road, Exeter, United Kingdom.
  • Dempster EL; University of Exeter Medical School, University of Exeter, Barrack Road, Exeter, United Kingdom.
  • Mansell G; University of Exeter Medical School, University of Exeter, Barrack Road, Exeter, United Kingdom.
  • Burrage J; University of Exeter Medical School, University of Exeter, Barrack Road, Exeter, United Kingdom.
  • Bass N; Division of Psychiatry, University College London, London, United Kingdom.
  • Bohlken MM; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Heidelberglaan, Utrecht, Netherlands.
  • Corvin A; Department of Psychiatry and Neuropsychiatric Genetics Research Group, Trinity Translational Medicine Institute, Trinity College Dublin, St. James Hospital, Dublin, Ireland.
  • Curtis CJ; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom.
  • Dempster D; NIHR BioResource Centre Maudsley, South London and Maudsley NHS Foundation Trust (SLaM), King's College London, London, United Kingdom.
  • Di Forti M; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom.
  • Dinan TG; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom.
  • Donohoe G; South London and Maudsley NHS Mental Health Foundation Trust, London, United Kingdom.
  • Gaughran F; National Institute for Health Research (NIHR), Mental Health Biomedical Research Centre, South London and Maudsley NHS Foundation Trust and King's College London, London, United Kingdom.
  • Gill M; APC Microbiome Ireland, University College Cork, Cork, Ireland.
  • Gillespie A; Centre for Neuroimaging and Cognitive Genomics (NICOG), School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland.
  • Gunasinghe C; Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom.
  • Hulshoff HE; National Psychosis Service, South London and Maudsley NHS Foundation Trust, London, United Kingdom.
  • Hultman CM; Department of Psychiatry and Neuropsychiatric Genetics Research Group, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.
  • Johansson V; Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom.
  • Kahn RS; Department of Psychiatry, Medical Sciences Division, University of Oxford, Oxford, United Kingdom.
  • Kaprio J; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom.
  • Kenis G; Department of Psychiatry, University Medical Center Utrecht, Utrecht, Netherlands.
  • Kowalec K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • MacCabe J; Department of Medical Epidemiology and Biostatistics Sweden, Karolinska Institutet, Stockholm, Sweden.
  • McDonald C; Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm Health Care Services, Stockholm, Sweden.
  • McQuillin A; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands.
  • Morris DW; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, United States.
  • Murphy KC; Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland.
  • Mustard CJ; Department of Public Health, University of Helsinki, Helsinki, Finland.
  • Nenadic I; Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.
  • O'Donovan MC; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Quattrone D; College of Pharmacy, University of Manitoba, Winnipeg, Canada.
  • Richards AL; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom.
  • Rutten BP; Centre for Neuroimaging and Cognitive Genomics (NICOG), School of Medicine, National University of Ireland Galway, Galway, Ireland.
  • St Clair D; Division of Psychiatry, University College London, London, United Kingdom.
  • Therman S; Division of Psychiatry, University College London, London, United Kingdom.
  • Toulopoulou T; Centre for Neuroimaging and Cognitive Genomics (NICOG), School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland.
  • Van Os J; Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Waddington JL; Division of Biomedical Sciences, Institute of Health Research and Innovation, University of the Highlands and Islands, Inverness, United Kingdom.
  • Sullivan P; MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, United Kingdom.
  • Vassos E; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom.
  • Breen G; South London and Maudsley NHS Mental Health Foundation Trust, London, United Kingdom.
  • Collier DA; MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, United Kingdom.
  • Murray RM; Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.
  • Schalkwyk LS; The Institute of Medical Sciences, Univeristy of Aberdeen, Aberdeen, United Kingdom.
  • Mill J; Department of Public Health Solutions, Mental Health Unit, National Institute for Health and Welfare, Helsinki, Finland.
Elife ; 102021 02 26.
Article em En | MEDLINE | ID: mdl-33646943
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Metilação de DNA / Epigenoma / Esquizofrenia Resistente ao Tratamento Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Ano de publicação: 2021 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Metilação de DNA / Epigenoma / Esquizofrenia Resistente ao Tratamento Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Ano de publicação: 2021 Tipo de documento: Article