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TGF-ß-induced cell motility requires downregulation of ARHGAPs to sustain Rac1 activity.
Motizuki, Mitsuyoshi; Koinuma, Daizo; Yokoyama, Takashi; Itoh, Yuka; Omata, Chiho; Miyazono, Kohei; Saitoh, Masao; Miyazawa, Keiji.
Afiliação
  • Motizuki M; Department of Biochemistry, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
  • Koinuma D; Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Yokoyama T; Department of Biochemistry, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
  • Itoh Y; Department of Biochemistry, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
  • Omata C; Department of Biochemistry, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
  • Miyazono K; Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Saitoh M; Department of Biochemistry, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan; Center for Medical Education and Science, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
  • Miyazawa K; Department of Biochemistry, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan. Electronic address: kmiyazawa@yamanashi.ac.jp.
J Biol Chem ; 296: 100545, 2021.
Article em En | MEDLINE | ID: mdl-33741342
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Movimento Celular / Fator de Crescimento Transformador beta / Proteínas rac1 de Ligação ao GTP / Proteínas Ativadoras de GTPase / Proteína Smad3 / Transição Epitelial-Mesenquimal Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Movimento Celular / Fator de Crescimento Transformador beta / Proteínas rac1 de Ligação ao GTP / Proteínas Ativadoras de GTPase / Proteína Smad3 / Transição Epitelial-Mesenquimal Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article