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Hepatotoxicological potential of P-toluic acid in humanised-liver mice investigated using simplified physiologically based pharmacokinetic models.
Miura, Tomonori; Kamiya, Yusuke; Uehara, Shotaro; Murayama, Norie; Shimizu, Makiko; Suemizu, Hiroshi; Yamazaki, Hiroshi.
Afiliação
  • Miura T; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Japan.
  • Kamiya Y; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Japan.
  • Uehara S; Laboratory Animal Research Department, Central Institute for Experimental Animals, Kawasaki, Japan.
  • Murayama N; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Japan.
  • Shimizu M; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Japan.
  • Suemizu H; Laboratory Animal Research Department, Central Institute for Experimental Animals, Kawasaki, Japan.
  • Yamazaki H; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Japan.
Xenobiotica ; 51(6): 636-642, 2021 Jun.
Article em En | MEDLINE | ID: mdl-33781181
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fígado / Modelos Biológicos Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fígado / Modelos Biológicos Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article