Excitation of medium spiny neurons by 'inhibitory' ultrapotent chemogenetics via shifts in chloride reversal potential.

Gantz, Stephanie C; Ortiz, Maria M; Belilos, Andrew J; Moussawi, Khaled

Gantz, Stephanie C; Ortiz, Maria M; Belilos, Andrew J; Moussawi, Khaled.

Afiliação

Gantz SC; Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, United States.
Ortiz MM; Biological and Biomedical Neuroscience Program, University of North Carolina, Chapel Hill, United States.
Belilos AJ; National Institute on Drug Abuse, Baltimore, United States.
Moussawi K; National Institute on Drug Abuse, Baltimore, United States.

Elife ; 102021 04 06.

Article em En | MEDLINE | ID: mdl-33822716

Assuntos

Cloretos/metabolismo; Neurônios/metabolismo; Receptores de Dopamina D1/metabolismo; Receptores de Glicina/metabolismo; Estriado Ventral/metabolismo; Receptor Nicotínico de Acetilcolina alfa7/metabolismo; Animais; Feminino; Masculino; Camundongos; Técnicas de Patch-Clamp; Receptores de GABA-A/metabolismo

Palavras-chave

D1 medium spiny neuron; PSAM; chemogenetics; chloride permeability; mouse; neuroscience; uPSEM

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cloretos / Receptores de Dopamina D1 / Receptores de Glicina / Receptor Nicotínico de Acetilcolina alfa7 / Estriado Ventral / Neurônios Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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