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Splice it up: Atypical transcripts to boost leukemia immunotherapy.
Cieri, Nicoletta; Wu, Catherine J.
Afiliação
  • Cieri N; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
  • Wu CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: cwu@partners.org.
Immunity ; 54(4): 608-610, 2021 04 13.
Article em En | MEDLINE | ID: mdl-33852826
ABSTRACT
Neoantigens are prime targets for cancer immunotherapy, but their identification in low mutational burden malignancies remains challenging. In this issue of Immunity, Ehx et al. show that atypical transcripts, and particularly retained introns, expand the spectrum of leukemia immunotherapy targets.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article