Mitochondrial Metabolism Regulation of T Cell-Mediated Immunity.
Annu Rev Immunol
; 39: 395-416, 2021 04 26.
Article
em En
| MEDLINE
| ID: mdl-33902315
ABSTRACT
Recent evidence supports the notion that mitochondrial metabolism is necessary for T cell activation, proliferation, and function. Mitochondrial metabolism supports T cell anabolism by providing key metabolites for macromolecule synthesis and generating metabolites for T cell function. In this review, we focus on how mitochondrial metabolism controls conventional and regulatory T cell fates and function.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Imunidade Celular
/
Mitocôndrias
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article