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Pharmacokinetics and safety of rucaparib in patients with advanced solid tumors and hepatic impairment.
Grechko, Nikolay; Skarbova, Viera; Tomaszewska-Kiecana, Monika; Ramlau, Rodryg; Centkowski, Piotr; Drew, Yvette; Dziadziuszko, Rafal; Zemanova, Milada; Beltman, Jeri; Nash, Eileen; Habeck, Jenn; Liao, Mingxiang; Xiao, Jim.
Afiliação
  • Grechko N; Clinical Science, Clovis Oncology UK Ltd., Cambridge, UK.
  • Skarbova V; Department of Internal Medicine and Clinical Pharmacology, Summit Clinical Research, Bratislava, Slovakia.
  • Tomaszewska-Kiecana M; BioVirtus Centrum Medyczne, Jozefow, Poland.
  • Ramlau R; Department of Oncology and Pulmonology, Poznan University of Medical Sciences, Poznan, Poland.
  • Centkowski P; Department of Oncology, Provincial Specialist Hospital in Biala Podlaska, Biala Podlaska, Poland.
  • Drew Y; Clinical and Translational Institute, Newcastle University, Newcastle Upon Tyne, UK.
  • Dziadziuszko R; Department of Oncology and Radiotherapy and Early Clinical Trials Unit, Medical University of Gdansk, Gdansk, Poland.
  • Zemanova M; Department of Oncology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
  • Beltman J; Regulatory Affairs, Clovis Oncology, Inc., Boulder, CO, USA.
  • Nash E; Clinical Operations, Clovis Oncology, Inc., Boulder, CO, USA.
  • Habeck J; Biostatistics, Clovis Oncology, Inc., Boulder, CO, USA.
  • Liao M; Clinical Pharmacology, Clovis Oncology, Inc., 5500 Flatiron Pkwy, Boulder, CO, 80301, USA.
  • Xiao J; Clinical Pharmacology, Clovis Oncology, Inc., 5500 Flatiron Pkwy, Boulder, CO, 80301, USA. jxiao@clovisoncology.com.
Cancer Chemother Pharmacol ; 88(2): 259-270, 2021 08.
Article em En | MEDLINE | ID: mdl-33909097
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Poli(ADP-Ribose) Polimerases / Indóis / Hepatopatias / Neoplasias Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Poli(ADP-Ribose) Polimerases / Indóis / Hepatopatias / Neoplasias Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article