Bidirectional association of neurodevelopment with growth: a prospective cohort study.
BMC Pediatr
; 21(1): 203, 2021 04 28.
Article
em En
| MEDLINE
| ID: mdl-33910531
ABSTRACT
BACKGROUND:
The study aims to use the cross-lagged model and utilize data from the Born in Shenyang Cohort Study to characterize the bidirectional associations of the term-born infants' neurodevelopment in five domains and physical growth in early life.METHOD:
This study consists of 688 mother-child dyads from the Born in Shenyang Cohort Study. Infants' anthropometric (weight and length) and development in neurological outcomes (Gesell Development Scale) were measured at the age of 6 and 12 months. Cross-lagged analyses and multiple linear regression analyses were used to explore the longitudinal relationships in both directions.RESULTS:
In terms of longitudinal studies, the inverse associations between infants' two skills (gross motor and social behavior) at the age of 6 months with BMI Z -scores at the age of 12 months (gross motor aß = - 0.20, 95% CI - 0.31 to- 0.09; social behavior aß = - 0.23, 95% CI - 0.33 to- 0.13) were found. Conversely, a higher infant Z -scored BMI at the age of 6 months predicted a lower gross motor at the age of 12 months (aß = - 0.08, 95% CI - 0.12 to- 0.04). In cross-lagged analyses, an adverse association in both directions between gross motor and Z -scored BMI was observed.CONCLUSION:
We found bidirectional relationships between infants' neurodevelopment of gross motor with physical growth and suggested the term-born infants, who are on the edge of the developmental danger, should not be overlooked.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Desenvolvimento Infantil
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
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Prognostic_studies
Limite:
Child
/
Humans
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Infant
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article