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Improvement of Oral Bioavailability of Pyrazolo-Pyridone Inhibitors of the Interaction of DCN1/2 and UBE2M.
Kim, Ho Shin; Hammill, Jared T; Scott, Daniel C; Chen, Yizhe; Rice, Amy L; Pistel, William; Singh, Bhuvanesh; Schulman, Brenda A; Guy, R Kiplin.
Afiliação
  • Kim HS; Department of Pharmaceutical Sciences, University of Kentucky, Lexington, Kentucky 40508, United States.
  • Hammill JT; Department of Pharmaceutical Sciences, University of Kentucky, Lexington, Kentucky 40508, United States.
  • Scott DC; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Chen Y; Department of Pharmaceutical Sciences, University of Kentucky, Lexington, Kentucky 40508, United States.
  • Rice AL; Department of Pharmaceutical Sciences, University of Kentucky, Lexington, Kentucky 40508, United States.
  • Pistel W; Department of Pharmaceutical Sciences, University of Kentucky, Lexington, Kentucky 40508, United States.
  • Singh B; Department of Surgery, Laboratory of Epithelial Cancer Biology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.
  • Schulman BA; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Guy RK; Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried 82152, Germany.
J Med Chem ; 64(9): 5850-5862, 2021 05 13.
Article em En | MEDLINE | ID: mdl-33945681
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Piridinas / Enzimas de Conjugação de Ubiquitina / Peptídeos e Proteínas de Sinalização Intracelular Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Piridinas / Enzimas de Conjugação de Ubiquitina / Peptídeos e Proteínas de Sinalização Intracelular Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article