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The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients.
Abbott, Keene L; Vander Heiden, Matthew G.
Afiliação
  • Abbott KL; Koch Institute for Integrative Cancer Research and the Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Vander Heiden MG; Koch Institute for Integrative Cancer Research and the Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. mvh@mit.edu.
BMC Biol ; 19(1): 92, 2021 05 10.
Article em En | MEDLINE | ID: mdl-33966629
ABSTRACT
The extent to which tumors acquire nutrients from dietary sources as opposed to from the breakdown of host tissues is not known. In this issue of BMC Biology, Holland et al. report an approach where food sources with different isotope labeled carbon ratios can be used to answer this question, and find that tumors arising in Drosophila melanogaster procure most of their nutrients from the host.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Drosophila melanogaster / Neoplasias Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Drosophila melanogaster / Neoplasias Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article