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Systemic administration of ivabradine, a hyperpolarization-activated cyclic nucleotide-gated channel inhibitor, blocks spontaneous absence seizures.
Iacone, Yasmine; Morais, Tatiana P; David, François; Delicata, Francis; Sandle, Joanna; Raffai, Timea; Parri, Harri Rheinallt; Weisser, Johan Juhl; Bundgaard, Christoffer; Klewe, Ib Vestergaard; Tamás, Gábor; Thomsen, Morten Skøtt; Crunelli, Vincenzo; Lorincz, Magor L.
Afiliação
  • Iacone Y; Neuroscience Research, H. Lundbeck A/S, Valby, Copenhagen, Denmark.
  • Morais TP; Biomedical Sciences, Faculty of Health and Medical Sciences, Copenhagen University, Copenhagen, Denmark.
  • David F; Neuroscience Division, School of Biosciences, Cardiff University, Cardiff, UK.
  • Delicata F; Integrative Neuroscience and Cognition Center, University of Paris, Paris, France.
  • Sandle J; School of Life and Health Sciences, Aston University, Birmingham, UK.
  • Raffai T; Department of Anatomy, Physiology, and Neuroscience, MTA-SZTE Research Group for Cortical Microcircuits, University of Szeged, Szeged, Hungary.
  • Parri HR; Department of Physiology, Anatomy, and Neuroscience, Faculty of Sciences, University of Szeged, Szeged, Hungary.
  • Weisser JJ; Department of Physiology, Faculty of Medicine, University of Szeged, Szeged, Hungary.
  • Bundgaard C; School of Life and Health Sciences, Aston University, Birmingham, UK.
  • Klewe IV; Neuroscience Research, H. Lundbeck A/S, Valby, Copenhagen, Denmark.
  • Tamás G; Neuroscience Research, H. Lundbeck A/S, Valby, Copenhagen, Denmark.
  • Thomsen MS; Neuroscience Research, H. Lundbeck A/S, Valby, Copenhagen, Denmark.
  • Crunelli V; Department of Anatomy, Physiology, and Neuroscience, MTA-SZTE Research Group for Cortical Microcircuits, University of Szeged, Szeged, Hungary.
  • Lorincz ML; Neuroscience Research, H. Lundbeck A/S, Valby, Copenhagen, Denmark.
Epilepsia ; 62(7): 1729-1743, 2021 07.
Article em En | MEDLINE | ID: mdl-34018186
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Convulsões / Canais de Cátion Regulados por Nucleotídeos Cíclicos / Ivabradina / Anticonvulsivantes Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Convulsões / Canais de Cátion Regulados por Nucleotídeos Cíclicos / Ivabradina / Anticonvulsivantes Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article