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Large-scale plasma proteomic profiling identifies a high-performance biomarker panel for Alzheimer's disease screening and staging.
Jiang, Yuanbing; Zhou, Xiaopu; Ip, Fanny C; Chan, Philip; Chen, Yu; Lai, Nicole C H; Cheung, Kit; Lo, Ronnie M N; Tong, Estella P S; Wong, Bonnie W Y; Chan, Andrew L T; Mok, Vincent C T; Kwok, Timothy C Y; Mok, Kin Y; Hardy, John; Zetterberg, Henrik; Fu, Amy K Y; Ip, Nancy Y.
Afiliação
  • Jiang Y; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, China.
  • Zhou X; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, China.
  • Ip FC; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.
  • Chan P; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development; Shenzhen-Hong Kong Institute of Brain Science, HKUST Shenzhen Research Institute, Shenzhen, China.
  • Chen Y; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, China.
  • Lai NCH; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.
  • Cheung K; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development; Shenzhen-Hong Kong Institute of Brain Science, HKUST Shenzhen Research Institute, Shenzhen, China.
  • Lo RMN; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, China.
  • Tong EPS; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, China.
  • Wong BWY; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.
  • Chan ALT; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development; Shenzhen-Hong Kong Institute of Brain Science, HKUST Shenzhen Research Institute, Shenzhen, China.
  • Mok VCT; The Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, China.
  • Kwok TCY; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, China.
  • Mok KY; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, China.
  • Hardy J; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, China.
  • Zetterberg H; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, China.
  • Fu AKY; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, China.
  • Ip NY; Divisions of Neurology and Geriatrics, Department of Medicine, Queen Elizabeth Hospital, Hong Kong, China.
Alzheimers Dement ; 18(1): 88-102, 2022 01.
Article em En | MEDLINE | ID: mdl-34032364
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biomarcadores / Programas de Rastreamento / Peptídeos beta-Amiloides / Proteínas tau / Proteômica / Doença de Alzheimer Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Aged / Humans / Middle aged País/Região como assunto: Asia Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biomarcadores / Programas de Rastreamento / Peptídeos beta-Amiloides / Proteínas tau / Proteômica / Doença de Alzheimer Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Aged / Humans / Middle aged País/Região como assunto: Asia Idioma: En Ano de publicação: 2022 Tipo de documento: Article