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Tocilizumab is safe and tolerable and reduces C-reactive protein concentrations in the plasma and cerebrospinal fluid of ALS patients.
Milligan, Carol; Atassi, Nazem; Babu, Suma; Barohn, Richard J; Caress, James B; Cudkowicz, Merit E; Evora, Armineuza; Hawkins, Gregory A; Wosiski-Kuhn, Marlena; Macklin, Eric A; Shefner, Jeremy M; Simmons, Zachary; Bowser, Robert P; Ladha, Shafeeq S.
Afiliação
  • Milligan C; Department of Neurobiology and Anatomy, Wake Forest University, Winston-Salem, North Carolina, USA.
  • Atassi N; Department of Neurology, Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Babu S; Department of Neurology, Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Barohn RJ; Department of Neurology, Kansas University, Kansas City, Kansas, USA.
  • Caress JB; Department of Neurology, Wake Forest University, Winston-Salem, North Carolina, USA.
  • Cudkowicz ME; Department of Neurology, Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Evora A; Department of Neurology, Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Hawkins GA; Department of Biochemistry and Center for Precision Medicine, Wake Forest University, Winston-Salem, North Carolina, USA.
  • Wosiski-Kuhn M; Department of Neurobiology and Anatomy, Wake Forest University, Winston-Salem, North Carolina, USA.
  • Macklin EA; Department of Medicine, Biostatistics Center, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Shefner JM; Department of Neurology, Gregory W. Fulton ALS and Neuromuscular Disease Center, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
  • Simmons Z; Department of Neurology, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA.
  • Bowser RP; Departments of Neurology and Neurobiology, Gregory W. Fulton ALS and Neuromuscular Disease Center, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
  • Ladha SS; Department of Neurology, Gregory W. Fulton ALS and Neuromuscular Disease Center, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
Muscle Nerve ; 64(3): 309-320, 2021 09.
Article em En | MEDLINE | ID: mdl-34075589
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína C-Reativa / Citocinas / Anticorpos Monoclonais Humanizados / Esclerose Lateral Amiotrófica / Anti-Inflamatórios Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína C-Reativa / Citocinas / Anticorpos Monoclonais Humanizados / Esclerose Lateral Amiotrófica / Anti-Inflamatórios Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article