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SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression.
Zhou, Haibin; Bai, Longchuan; Xu, Renqi; McEachern, Donna; Chinnaswamy, Krishnapriya; Li, Ruiting; Wen, Bo; Wang, Mi; Yang, Chao-Yie; Meagher, Jennifer L; Sun, Duxin; Stuckey, Jeanne A; Wang, Shaomeng.
Afiliação
  • Zhou H; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Bai L; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Xu R; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • McEachern D; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Chinnaswamy K; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Li R; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Wen B; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Wang M; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Yang CY; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Meagher JL; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Sun D; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Stuckey JA; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Wang S; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
ACS Med Chem Lett ; 12(6): 996-1004, 2021 Jun 10.
Article em En | MEDLINE | ID: mdl-34141084

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article