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Acute cell stress screen with supervised machine learning predicts cytotoxicity of excipients.
Bieberich, Andrew A; Rajwa, Bartek; Irvine, Allison; Fatig, Raymond O; Fekete, Alexander; Jin, Hong; Kutlina, Elena; Urban, Laszlo.
Afiliação
  • Bieberich AA; AsedaSciences Inc., 1281 Win Hentschel Boulevard, West Lafayette, IN 47906, USA. Electronic address: andrew.bieberich@asedasciences.com.
  • Rajwa B; Bindley Bioscience Center, Purdue University, West Lafayette, IN 47906, USA. Electronic address: brajwa@purdue.edu.
  • Irvine A; AsedaSciences Inc., 1281 Win Hentschel Boulevard, West Lafayette, IN 47906, USA. Electronic address: allison.irvine@asedasciences.com.
  • Fatig RO; AsedaSciences Inc., 1281 Win Hentschel Boulevard, West Lafayette, IN 47906, USA. Electronic address: raymond.fatig@asedasciences.com.
  • Fekete A; Preclinical Safety, Translational Medicine, Novartis Institutes of Biomedical Research, Cambridge, MA, 02139, USA. Electronic address: alexander.fekete@novartis.com.
  • Jin H; Preclinical Safety, Translational Medicine, Novartis Institutes of Biomedical Research, Cambridge, MA, 02139, USA. Electronic address: hong.jin@novartis.com.
  • Kutlina E; Preclinical Safety, Translational Medicine, Novartis Institutes of Biomedical Research, Cambridge, MA, 02139, USA. Electronic address: elena.kutlina@novartis.com.
  • Urban L; Preclinical Safety, Translational Medicine, Novartis Institutes of Biomedical Research, Cambridge, MA, 02139, USA. Electronic address: laszlo.urban@novartis.com.
J Pharmacol Toxicol Methods ; 111: 107088, 2021.
Article em En | MEDLINE | ID: mdl-34144174
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Conservantes Farmacêuticos / Excipientes Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Conservantes Farmacêuticos / Excipientes Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article