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Anti-Siglec-15 antibody suppresses bone resorption by inhibiting osteoclast multinucleation without attenuating bone formation.
Tsukazaki, Hiroyuki; Kikuta, Junichi; Ao, Tomoka; Morimoto, Akito; Fukuda, Chie; Tsuda, Eisuke; Minoshima, Masafumi; Kikuchi, Kazuya; Kaito, Takashi; Ishii, Masaru.
Afiliação
  • Tsukazaki H; Department of Immunology and Cell Biology, Graduate School of Medicine & Frontier Biosciences, Osaka University, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan; Department of Orthopedic Surgery, Graduate School of Medicine, Osaka University, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan.
  • Kikuta J; Department of Immunology and Cell Biology, Graduate School of Medicine & Frontier Biosciences, Osaka University, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan; WPI-Immunology Frontier Research Center, Osaka University, Osaka, Japan; Laboratory of Bioimaging and Drug Discovery, National Institutes
  • Ao T; Department of Immunology and Cell Biology, Graduate School of Medicine & Frontier Biosciences, Osaka University, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan; Laboratory of Bioimaging and Drug Discovery, National Institutes of Biomedical Innovation, Health and Nutrition, 7-6-8 Saito-Asagi, Ibara
  • Morimoto A; Department of Immunology and Cell Biology, Graduate School of Medicine & Frontier Biosciences, Osaka University, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan.
  • Fukuda C; Specialty Medicine Research Laboratories I, Daiichi Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan.
  • Tsuda E; Specialty Medicine Research Laboratories I, Daiichi Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan.
  • Minoshima M; Department of Material and Life Sciences, Graduate School of Engineering, Osaka University, 2-1 Yamada-oka, Suita, Osaka 565-0871, Japan.
  • Kikuchi K; WPI-Immunology Frontier Research Center, Osaka University, Osaka, Japan; Department of Material and Life Sciences, Graduate School of Engineering, Osaka University, 2-1 Yamada-oka, Suita, Osaka 565-0871, Japan.
  • Kaito T; Department of Orthopedic Surgery, Graduate School of Medicine, Osaka University, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan.
  • Ishii M; Department of Immunology and Cell Biology, Graduate School of Medicine & Frontier Biosciences, Osaka University, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan; WPI-Immunology Frontier Research Center, Osaka University, Osaka, Japan; Laboratory of Bioimaging and Drug Discovery, National Institutes
Bone ; 152: 116095, 2021 11.
Article em En | MEDLINE | ID: mdl-34216837
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoclastos / Reabsorção Óssea Limite: Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoclastos / Reabsorção Óssea Limite: Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article