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Discovery of novel tubulin inhibitors targeting taxanes site by virtual screening, molecular dynamic simulation, and biological evaluation.
Zhang, Hui; Mao, Jun; Yang, Yan-Li; Liu, Chun-Tao; Shen, Chen; Zhang, Hong-Rui; Xie, Huan-Zhang; Ding, Lan.
Afiliação
  • Zhang H; Department of Pharmaceutical Engineering, College of Life Science, Northwest Normal University, Lanzhou, Gansu, China.
  • Mao J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
  • Yang YL; Department of Pharmaceutical Engineering, College of Life Science, Northwest Normal University, Lanzhou, Gansu, China.
  • Liu CT; Department of Pharmaceutical Engineering, College of Life Science, Northwest Normal University, Lanzhou, Gansu, China.
  • Shen C; Department of Pharmaceutical Engineering, College of Life Science, Northwest Normal University, Lanzhou, Gansu, China.
  • Zhang HR; Department of Pharmaceutical Engineering, College of Life Science, Northwest Normal University, Lanzhou, Gansu, China.
  • Xie HZ; Department of Pharmaceutical Engineering, College of Life Science, Northwest Normal University, Lanzhou, Gansu, China.
  • Ding L; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
J Cell Biochem ; 122(11): 1609-1624, 2021 11.
Article em En | MEDLINE | ID: mdl-34237164
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tubulina (Proteína) / Taxoides / Moduladores de Tubulina Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tubulina (Proteína) / Taxoides / Moduladores de Tubulina Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article