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Genome-scale screens identify factors regulating tumor cell responses to natural killer cells.
Sheffer, Michal; Lowry, Emily; Beelen, Nicky; Borah, Minasri; Amara, Suha Naffar-Abu; Mader, Chris C; Roth, Jennifer A; Tsherniak, Aviad; Freeman, Samuel S; Dashevsky, Olga; Gandolfi, Sara; Bender, Samantha; Bryan, Jordan G; Zhu, Cong; Wang, Li; Tariq, Ifrah; Kamath, Govinda M; Simoes, Ricardo De Matos; Dhimolea, Eugen; Yu, Channing; Hu, Yiguo; Dufva, Olli; Giannakis, Marios; Syrgkanis, Vasilis; Fraenkel, Ernest; Golub, Todd; Romee, Rizwan; Mustjoki, Satu; Culhane, Aedin C; Wieten, Lotte; Mitsiades, Constantine S.
Afiliação
  • Sheffer M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. Michal_Sheffer@dfci.havard.edu.
  • Lowry E; Department of Medicine, Harvard Medical School, Boston, MA, USA. Michal_Sheffer@dfci.havard.edu.
  • Beelen N; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA. Michal_Sheffer@dfci.havard.edu.
  • Borah M; Ludwig Center, Harvard Medical School, Boston, MA, USA. Michal_Sheffer@dfci.havard.edu.
  • Amara SN; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Mader CC; Department of Transplantation Immunology, Maastricht University Medical Center+, Maastricht, the Netherlands.
  • Roth JA; School for Oncology and Developmental Biology, Maastricht University Medical Center+ GROW, Maastricht, the Netherlands.
  • Tsherniak A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Freeman SS; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
  • Dashevsky O; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Gandolfi S; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Bender S; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Bryan JG; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Zhu C; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Wang L; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Tariq I; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Kamath GM; Ludwig Center, Harvard Medical School, Boston, MA, USA.
  • Simoes RM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Dhimolea E; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Yu C; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Hu Y; Ludwig Center, Harvard Medical School, Boston, MA, USA.
  • Dufva O; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Giannakis M; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Syrgkanis V; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Fraenkel E; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Golub T; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Romee R; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Mustjoki S; Microsoft Research, Cambridge, MA, USA.
  • Culhane AC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Wieten L; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Mitsiades CS; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
Nat Genet ; 53(8): 1196-1206, 2021 08.
Article em En | MEDLINE | ID: mdl-34253920

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Regulação Neoplásica da Expressão Gênica / Resistencia a Medicamentos Antineoplásicos / Citotoxicidade Imunológica / Inibidores de Checkpoint Imunológico Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Regulação Neoplásica da Expressão Gênica / Resistencia a Medicamentos Antineoplásicos / Citotoxicidade Imunológica / Inibidores de Checkpoint Imunológico Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article