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Efficient Inhibition of SARS-CoV-2 Using Chimeric Antisense Oligonucleotides through RNase L Activation*.
Su, Xiaoxuan; Ma, Wenxiao; Feng, Di; Cheng, Boyang; Wang, Qian; Guo, Zefeng; Zhou, Demin; Tang, Xinjing.
Afiliação
  • Su X; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, No. 38, Xueyuan Road, Beijing, 100191, China.
  • Ma W; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, No. 38, Xueyuan Road, Beijing, 100191, China.
  • Feng D; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, No. 38, Xueyuan Road, Beijing, 100191, China.
  • Cheng B; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, No. 38, Xueyuan Road, Beijing, 100191, China.
  • Wang Q; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, No. 38, Xueyuan Road, Beijing, 100191, China.
  • Guo Z; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, No. 38, Xueyuan Road, Beijing, 100191, China.
  • Zhou D; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, No. 38, Xueyuan Road, Beijing, 100191, China.
  • Tang X; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, No. 38, Xueyuan Road, Beijing, 100191, China.
Angew Chem Int Ed Engl ; 60(40): 21662-21667, 2021 09 27.
Article em En | MEDLINE | ID: mdl-34278671
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Oligonucleotídeos Antissenso / Endorribonucleases / Ativação Enzimática / SARS-CoV-2 Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Oligonucleotídeos Antissenso / Endorribonucleases / Ativação Enzimática / SARS-CoV-2 Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article