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Gut Microbiome Modulation by Antibiotics in Adult Asthma: A Human Proof-of-Concept Intervention Trial.
Van Engelen, Tjitske S R; Yang, Jack; Haak, Bastiaan W; Bonta, Peter I; Van Der Poll, Tom; Wiersinga, W Joost.
Afiliação
  • Van Engelen TSR; Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands. Electronic address: t.s.vanengelen@amsterdamumc.nl.
  • Yang J; Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Haak BW; Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Bonta PI; Department of Respiratory Medicine, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Van Der Poll T; Center for Experimental and Molecular Medicine, Department of Internal Medicine, Division of Infectious disease, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Wiersinga WJ; Center for Experimental and Molecular Medicine, Department of Internal Medicine, Division of Infectious disease, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
Clin Gastroenterol Hepatol ; 20(6): 1404-1407.e4, 2022 06.
Article em En | MEDLINE | ID: mdl-34303860
ABSTRACT
Although the pathophysiology of asthma is complex, perturbation of the gut microbiota has been associated with an increased risk of asthma development in childhood.1 Disruption and subsequent dysregulation of gut microbiota-related immunologic processes have also been linked to disease severity and response to treatment.2.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Microbioma Gastrointestinal Limite: Adult / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Microbioma Gastrointestinal Limite: Adult / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article