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An Activity-Based Probe for Cathepsin K Imaging with Excellent Potency and Selectivity.
Lemke, Carina; Benýsek, Jakub; Brajtenbach, Dominik; Breuer, Christian; Jílková, Adéla; Horn, Martin; Busa, Michal; Ulrychová, Lenka; Illies, Annika; Kubatzky, Katharina F; Bartz, Ulrike; Mares, Michael; Gütschow, Michael.
Afiliação
  • Lemke C; Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, Bonn 53121, Germany.
  • Benýsek J; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo n. 2, Prague 16610, Czech Republic.
  • Brajtenbach D; First Faculty of Medicine, Charles University, Katerinská 32, Prague 12108, Czech Republic.
  • Breuer C; Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, Bonn 53121, Germany.
  • Jílková A; Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, Bonn 53121, Germany.
  • Horn M; Department of Natural Sciences, University of Applied Sciences Bonn-Rhein-Sieg, von-Liebig-Str. 20, Rheinbach 53359, Germany.
  • Busa M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo n. 2, Prague 16610, Czech Republic.
  • Ulrychová L; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo n. 2, Prague 16610, Czech Republic.
  • Illies A; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo n. 2, Prague 16610, Czech Republic.
  • Kubatzky KF; Department of Biochemistry, Faculty of Science, Charles University, Hlavova 8, Prague 12800, Czech Republic.
  • Bartz U; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo n. 2, Prague 16610, Czech Republic.
  • Mares M; Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, Bonn 53121, Germany.
  • Gütschow M; Department of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, Im Neuenheimer Feld 324, Heidelberg 69120, Germany.
J Med Chem ; 64(18): 13793-13806, 2021 09 23.
Article em En | MEDLINE | ID: mdl-34473502
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acrilamidas / Inibidores de Cisteína Proteinase / Catepsina K / Corantes Fluorescentes Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acrilamidas / Inibidores de Cisteína Proteinase / Catepsina K / Corantes Fluorescentes Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article