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Design, synthesis, and biological evaluation of novel pyrrolidinone small-molecule Formyl peptide receptor 2 agonists.
Maciuszek, Monika; Ortega-Gomez, Almudena; Maas, Sanne L; Garrido-Mesa, Jose; Ferraro, Bartolo; Perretti, Mauro; Merritt, Andy; Nicolaes, Gerry A F; Soehnlein, Oliver; Chapman, Timothy M.
Afiliação
  • Maciuszek M; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, UK; The William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK. Electronic address: maciuszekmonika@gmail.com.
  • Ortega-Gomez A; Institute for Cardiovascular Prevention (IPEK), LMU Munich Hospital, Munich, Germany.
  • Maas SL; Institute for Cardiovascular Prevention (IPEK), LMU Munich Hospital, Munich, Germany.
  • Garrido-Mesa J; The William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK.
  • Ferraro B; Institute for Cardiovascular Prevention (IPEK), LMU Munich Hospital, Munich, Germany.
  • Perretti M; The William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK.
  • Merritt A; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, UK.
  • Nicolaes GAF; CARIM - School for Cardiovascular Sciences Department of Biochemistry, Maastricht University, Maastricht, Netherlands.
  • Soehnlein O; Institute for Cardiovascular Prevention (IPEK), LMU Munich Hospital, Munich, Germany; Department of Physiology and Pharmacology (FyFa), Karolinska Institute, Stockholm, Sweden; Institute for Experimental Pathology (ExPat), Centre for Molecular Biology of Inflammation, University of Münster, Münster,
  • Chapman TM; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, UK.
Eur J Med Chem ; 226: 113805, 2021 Dec 15.
Article em En | MEDLINE | ID: mdl-34536667
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirrolidinonas / Desenho de Fármacos / Anti-Inflamatórios não Esteroides / Receptores de Lipoxinas / Receptores de Formil Peptídeo / Bibliotecas de Moléculas Pequenas Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirrolidinonas / Desenho de Fármacos / Anti-Inflamatórios não Esteroides / Receptores de Lipoxinas / Receptores de Formil Peptídeo / Bibliotecas de Moléculas Pequenas Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article