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Antifungal Susceptibility of 182 Fusarium Species Isolates from 20 European Centers: Comparison between EUCAST and Gradient Concentration Strip Methods.
Blaize, Marion; Normand, Anne-Cecile; Imbert, Sebastien; Al-Hatmi, Abdullah M S; Chryssanthou, Erja; Cassaing, Sophie; Schuttler, Christine; Hasseine, Lilia; Mahinc, Caroline; Costa, Damien; Bonnal, Christine; Ranque, Stéphane; Sautour, Marc; Rubio, Elisa; Delhaes, Laurence; Riat, Arnaud; Sendid, Boualem; Kristensen, Lise; Brandenberger, Marcel; Stubbe, Dirk; Brun, Sophie; Piarroux, Renaud; Fekkar, Arnaud.
Afiliação
  • Blaize M; AP-HP, Groupe Hospitalier La Pitié-Salpêtrière, Service de Parasitologie Mycologie, Paris, France.
  • Normand AC; Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses, CIMI-Paris, Paris, France.
  • Imbert S; AP-HP, Groupe Hospitalier La Pitié-Salpêtrière, Service de Parasitologie Mycologie, Paris, France.
  • Al-Hatmi AMS; AP-HP, Groupe Hospitalier La Pitié-Salpêtrière, Service de Parasitologie Mycologie, Paris, France.
  • Chryssanthou E; Centre of Expertise in Mycology, Radboud University Medical Centre, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
  • Cassaing S; Natural and Medical Sciences Research Center, Department of Microbiology, University of Nizwagrid.444752.4, Nizwa, Oman.
  • Schuttler C; Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden.
  • Hasseine L; CHU Toulouse, Service de Parasitologie-Mycologie, Toulouse, France.
  • Mahinc C; Laboratoire Biogroup-LCD, Levallois, France.
  • Costa D; CHU de Nice, Service de Parasitologie Mycologie, Nice, France.
  • Bonnal C; CHU de Saint-Etienne, Service de Parasitologie Mycologie, Saint-Etienne, France.
  • Ranque S; Centre Hospitalier Universitaire de Rouen, Service de Parasitologie Mycologie, Rouen, France.
  • Sautour M; AP-HP, Hôpital Bichat-Claude Bernard, Service de Parasitologie Mycologie, Paris, France.
  • Rubio E; Aix Marseille University, IRD, AP-HM, SSA, VITROME, IHU Méditerranée Infection, Marseille, France.
  • Delhaes L; CHU de Dijon, Service de Parasitologie Mycologie, Dijon, France.
  • Riat A; Department of Microbiology, ISGlobal Barcelona Institute for Global Health, Barcelona, Spain.
  • Sendid B; CDB, Hospital Clinic, University of Barcelona, Barcelona, Spain.
  • Kristensen L; CHU de Bordeaux, Groupe Hospitalier Pellegrin, Service de Mycologie, Bordeaux, France.
  • Brandenberger M; Geneva University Hospitals, Bacteriology Laboratory, Geneva, Switzerland.
  • Stubbe D; CHU de Lille, Department Parasitology-Mycology, Lille, France.
  • Brun S; Aarhus University Hospital, Department of Clinical Microbiology, Aarhus, Denmark.
  • Piarroux R; Labor Synlab Luzern, Lucerne, Switzerland.
  • Fekkar A; Sciensano, BCCM/IHEM Collection, Mycology and Aerobiology Unit, Brussels, Belgium.
Antimicrob Agents Chemother ; 65(12): e0149521, 2021 11 17.
Article em En | MEDLINE | ID: mdl-34543091
ABSTRACT
We determined the susceptibility of 182 Fusarium species isolates to five antifungal drugs (amphotericin B, voriconazole, posaconazole, isavuconazole, and terbinafine) by the EUCAST method. Based on the latest taxonomic insights, isolates collected from 20 European centers were distributed into seven complexes and 27 species. The susceptibility was variable, depending on the species. Comparison with the gradient concentration strip method, which was used for 77 isolates, showed essential agreement values for voriconazole, posaconazole, isavuconazole, and amphotericin B of 17%, 91%, 83%, and 70%, respectively.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fusarium / Antifúngicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fusarium / Antifúngicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article