Improved HDAC Inhibition, Stronger Cytotoxic Effect and Higher Selectivity against Leukemias and Lymphomas of Novel, Tricyclic Vorinostat Analogues.

Bieszczad, Bartosz; Garbicz, Damian; Switalska, Marta; Dudek, Marta K; Warszycki, Dawid; Wietrzyk, Joanna; Grzesiuk, Elzbieta; Mieczkowski, Adam.

Afiliação

Bieszczad B; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland.
Garbicz D; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland.
Switalska M; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114 Wroclaw, Poland.
Dudek MK; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363 Lodz, Poland.
Warszycki D; Maj Institute of Pharmacology, Polish Academy of Sciences, 31-343 Cracow, Poland.
Wietrzyk J; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114 Wroclaw, Poland.
Grzesiuk E; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland.
Mieczkowski A; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland.

Pharmaceuticals (Basel) ; 14(9)2021 Aug 26.

Article em En | MEDLINE | ID: mdl-34577551