Multiple Autonomous Cell Death Suppression Strategies Ensure Cytomegalovirus Fitness.

Mandal, Pratyusha; Nagrani, Lynsey N; Hernandez, Liliana; McCormick, Anita Louise; Dillon, Christopher P; Koehler, Heather S; Roback, Linda; Alnemri, Emad S; Green, Douglas R; Mocarski, Edward S

Mandal, Pratyusha; Nagrani, Lynsey N; Hernandez, Liliana; McCormick, Anita Louise; Dillon, Christopher P; Koehler, Heather S; Roback, Linda; Alnemri, Emad S; Green, Douglas R; Mocarski, Edward S.

Afiliação

Mandal P; Emory Vaccine Center, Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Nagrani LN; Pharmaceutical Product Development, Wilmington, NC 28401, USA.
Hernandez L; Emory Vaccine Center, Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.
McCormick AL; BioMarin Pharmaceuticals, Novato, CA 94949, USA.
Dillon CP; Pfizer, San Diego, CA 92121, USA.
Koehler HS; Emory Vaccine Center, Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Roback L; Emory Vaccine Center, Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Alnemri ES; Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Green DR; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Mocarski ES; Emory Vaccine Center, Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

Viruses ; 13(9)2021 08 27.

Article em En | MEDLINE | ID: mdl-34578288

Assuntos

Morte Celular; Muromegalovirus/genética; Muromegalovirus/fisiologia; Transdução de Sinais; Animais; Caspase 8/genética; Caspase 8/metabolismo; Macrófagos/virologia; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Endogâmicos C57BL; Mitocôndrias/metabolismo; Proteínas Virais/metabolismo

Palavras-chave

BCL2 family; DNA virus; HCMV; IFN; M36; M38.5; M41.1; M45; MCMV; RIPK1; RIPK3; TNF; UL36; apoptosis; cell death; cmvPCD; cytomegalovirus; extrinsic apoptosis; herpesvirus; inflammation; intrinsic apoptosis; macrophages; mitochondria; myeloid cells; necroptosis; pyroptosis; replication; serine protease; vIBO Caspase-8; vICA; vIRA; vMIA

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Morte Celular / Muromegalovirus Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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