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Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction.
Sakamoto, Keiko; Jin, Seon-Pil; Goel, Shubham; Jo, Jay-Hyun; Voisin, Benjamin; Kim, Doyoung; Nadella, Vinod; Liang, Hai; Kobayashi, Tetsuro; Huang, Xin; Deming, Clay; Horiuchi, Keisuke; Segre, Julia A; Kong, Heidi H; Nagao, Keisuke.
Afiliação
  • Sakamoto K; Cutaneous Leukocyte Biology Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Jin SP; Cutaneous Leukocyte Biology Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Goel S; Cutaneous Leukocyte Biology Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Jo JH; Cutaneous Microbiome and Inflammation Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Voisin B; Cutaneous Leukocyte Biology Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Kim D; Cutaneous Leukocyte Biology Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Nadella V; Cutaneous Leukocyte Biology Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Liang H; Cutaneous Microbiome and Inflammation Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Kobayashi T; Cutaneous Leukocyte Biology Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Huang X; Microbial Genomics Section, Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Deming C; Microbial Genomics Section, Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Horiuchi K; Department of Orthopedic Surgery, National Defense Medical College, Saitama 359-8513, Japan.
  • Segre JA; Microbial Genomics Section, Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Kong HH; Cutaneous Microbiome and Inflammation Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Nagao K; Cutaneous Leukocyte Biology Section, Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: keisuke.nagao@nih.gov.
Immunity ; 54(10): 2321-2337.e10, 2021 10 12.
Article em En | MEDLINE | ID: mdl-34582748
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pele / Linfócitos / Folículo Piloso / Receptores Notch / Secretases da Proteína Precursora do Amiloide / Disbiose / Proteína ADAM10 / Proteínas de Membrana Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pele / Linfócitos / Folículo Piloso / Receptores Notch / Secretases da Proteína Precursora do Amiloide / Disbiose / Proteína ADAM10 / Proteínas de Membrana Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article