Exercise Intervention Mitigates Pathological Liver Changes in NAFLD Zebrafish by Activating SIRT1/AMPK/NRF2 Signaling.

Zou, Yunyi; Chen, Zhanglin; Sun, Chenchen; Yang, Dong; Zhou, Zuoqiong; Peng, Xiyang; Zheng, Lan; Tang, Changfa

Zou, Yunyi; Chen, Zhanglin; Sun, Chenchen; Yang, Dong; Zhou, Zuoqiong; Peng, Xiyang; Zheng, Lan; Tang, Changfa.

Afiliação

Zou Y; Key Laboratory of Physical Fitness and Exercise Rehabilitation of Hunan Province, College of Physical Education, Hunan Normal University, Changsha 410012, China.
Chen Z; Key Laboratory of Physical Fitness and Exercise Rehabilitation of Hunan Province, College of Physical Education, Hunan Normal University, Changsha 410012, China.
Sun C; Key Laboratory of Physical Fitness and Exercise Rehabilitation of Hunan Province, College of Physical Education, Hunan Normal University, Changsha 410012, China.
Yang D; Key Laboratory of Physical Fitness and Exercise Rehabilitation of Hunan Province, College of Physical Education, Hunan Normal University, Changsha 410012, China.
Zhou Z; Key Laboratory of Physical Fitness and Exercise Rehabilitation of Hunan Province, College of Physical Education, Hunan Normal University, Changsha 410012, China.
Peng X; Key Laboratory of Physical Fitness and Exercise Rehabilitation of Hunan Province, College of Physical Education, Hunan Normal University, Changsha 410012, China.
Zheng L; Key Laboratory of Physical Fitness and Exercise Rehabilitation of Hunan Province, College of Physical Education, Hunan Normal University, Changsha 410012, China.
Tang C; Key Laboratory of Physical Fitness and Exercise Rehabilitation of Hunan Province, College of Physical Education, Hunan Normal University, Changsha 410012, China.

Int J Mol Sci ; 22(20)2021 Oct 10.

Article em En | MEDLINE | ID: mdl-34681600

Assuntos

Proteínas Quinases Ativadas por AMP/metabolismo; Fígado/patologia; Fator 2 Relacionado a NF-E2/metabolismo; Transdução de Sinais; Sirtuína 1/metabolismo; Animais; Antioxidantes; Dieta Hiperlipídica; Modelos Animais de Doenças; Feminino; Interleucina-1beta/metabolismo; Fígado/metabolismo; Masculino; Malondialdeído/metabolismo; NADPH Oxidase 4/metabolismo; Hepatopatia Gordurosa não Alcoólica/metabolismo; Hepatopatia Gordurosa não Alcoólica/patologia; Estresse Oxidativo; Condicionamento Físico Animal; Espécies Reativas de Oxigênio/metabolismo; Peixe-Zebra/metabolismo; Proteínas de Peixe-Zebra/metabolismo

Palavras-chave

NAFLD; ROS; SIRT1/AMPK/NRF2; exercise; zebrafish

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Fator 2 Relacionado a NF-E2 / Proteínas Quinases Ativadas por AMP / Sirtuína 1 / Fígado Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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