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Multimeric Anti-DR5 IgM Agonist Antibody IGM-8444 Is a Potent Inducer of Cancer Cell Apoptosis and Synergizes with Chemotherapy and BCL-2 Inhibitor ABT-199.
Wang, Beatrice T; Kothambawala, Tasnim; Wang, Ling; Matthew, Thomas J; Calhoun, Susan E; Saini, Avneesh K; Kotturi, Maya F; Hernandez, Genevive; Humke, Eric W; Peterson, Marvin S; Sinclair, Angus M; Keyt, Bruce A.
Afiliação
  • Wang BT; IGM Biosciences Inc., Mountain View, California.
  • Kothambawala T; IGM Biosciences Inc., Mountain View, California.
  • Wang L; IGM Biosciences Inc., Mountain View, California.
  • Matthew TJ; IGM Biosciences Inc., Mountain View, California.
  • Calhoun SE; IGM Biosciences Inc., Mountain View, California.
  • Saini AK; IGM Biosciences Inc., Mountain View, California.
  • Kotturi MF; IGM Biosciences Inc., Mountain View, California.
  • Hernandez G; IGM Biosciences Inc., Mountain View, California.
  • Humke EW; IGM Biosciences Inc., Mountain View, California.
  • Peterson MS; IGM Biosciences Inc., Mountain View, California.
  • Sinclair AM; IGM Biosciences Inc., Mountain View, California.
  • Keyt BA; IGM Biosciences Inc., Mountain View, California. bkeyt@igmbio.com.
Mol Cancer Ther ; 20(12): 2483-2494, 2021 12.
Article em En | MEDLINE | ID: mdl-34711645
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Imunoglobulina M / Compostos Bicíclicos Heterocíclicos com Pontes / Genes bcl-2 / Receptores do Ligante Indutor de Apoptose Relacionado a TNF / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Imunoglobulina M / Compostos Bicíclicos Heterocíclicos com Pontes / Genes bcl-2 / Receptores do Ligante Indutor de Apoptose Relacionado a TNF / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article