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Elevated circulating follistatin associates with an increased risk of type 2 diabetes.
Wu, Chuanyan; Borné, Yan; Gao, Rui; López Rodriguez, Maykel; Roell, William C; Wilson, Jonathan M; Regmi, Ajit; Luan, Cheng; Aly, Dina Mansour; Peter, Andreas; Machann, Jürgen; Staiger, Harald; Fritsche, Andreas; Birkenfeld, Andreas L; Tao, Rongya; Wagner, Robert; Canouil, Mickaël; Hong, Mun-Gwan; Schwenk, Jochen M; Ahlqvist, Emma; Kaikkonen, Minna U; Nilsson, Peter; Shore, Angela C; Khan, Faisel; Natali, Andrea; Melander, Olle; Orho-Melander, Marju; Nilsson, Jan; Häring, Hans-Ulrich; Renström, Erik; Wollheim, Claes B; Engström, Gunnar; Weng, Jianping; Pearson, Ewan R; Franks, Paul W; White, Morris F; Duffin, Kevin L; Vaag, Allan Arthur; Laakso, Markku; Stefan, Norbert; Groop, Leif; De Marinis, Yang.
Afiliação
  • Wu C; Department of Clinical Sciences, Lund University, Malmö, Sweden.
  • Borné Y; School of Control Science and Engineering, Shandong University, Jinan, Shandong, China.
  • Gao R; School of Intelligent Engineering, Shandong Management University, Jinan, Shandong, China.
  • López Rodriguez M; Department of Clinical Sciences, Lund University, Malmö, Sweden.
  • Roell WC; School of Control Science and Engineering, Shandong University, Jinan, Shandong, China.
  • Wilson JM; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.
  • Regmi A; A.I. Virtanen Institute for Molecular Sciences, Department of Biotechnology and Molecular Medicine, University of Eastern Finland, Kuopio, Finland.
  • Luan C; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA.
  • Aly DM; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA.
  • Peter A; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA.
  • Machann J; Department of Clinical Sciences, Lund University, Malmö, Sweden.
  • Staiger H; Department of Clinical Sciences, Lund University, Malmö, Sweden.
  • Fritsche A; Department of Internal Medicine IV, Division of Endocrinology, Diabetology and Nephrology; and Department for Diagnostic Laboratory Medicine, Institute for Clinical Chemistry and Pathobiochemistry, University Hospital Tübingen, University of Tübingen, Tübingen, Germany.
  • Birkenfeld AL; Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich, Tübingen, Germany.
  • Tao R; German Center for Diabetes Research (DZD), Tübingen, Germany.
  • Wagner R; Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich, Tübingen, Germany.
  • Canouil M; German Center for Diabetes Research (DZD), Tübingen, Germany.
  • Hong MG; Section of Experimental Radiology, Department of Radiology, University of Tübingen, Tübingen, Germany.
  • Schwenk JM; Department of Internal Medicine IV, Division of Endocrinology, Diabetology and Nephrology; and Department for Diagnostic Laboratory Medicine, Institute for Clinical Chemistry and Pathobiochemistry, University Hospital Tübingen, University of Tübingen, Tübingen, Germany.
  • Ahlqvist E; Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich, Tübingen, Germany.
  • Kaikkonen MU; German Center for Diabetes Research (DZD), Tübingen, Germany.
  • Nilsson P; Department of Internal Medicine IV, Division of Endocrinology, Diabetology and Nephrology; and Department for Diagnostic Laboratory Medicine, Institute for Clinical Chemistry and Pathobiochemistry, University Hospital Tübingen, University of Tübingen, Tübingen, Germany.
  • Shore AC; Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich, Tübingen, Germany.
  • Khan F; German Center for Diabetes Research (DZD), Tübingen, Germany.
  • Natali A; Department of Internal Medicine IV, Division of Endocrinology, Diabetology and Nephrology; and Department for Diagnostic Laboratory Medicine, Institute for Clinical Chemistry and Pathobiochemistry, University Hospital Tübingen, University of Tübingen, Tübingen, Germany.
  • Melander O; Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich, Tübingen, Germany.
  • Orho-Melander M; German Center for Diabetes Research (DZD), Tübingen, Germany.
  • Nilsson J; Division of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Häring HU; Department of Internal Medicine IV, Division of Endocrinology, Diabetology and Nephrology; and Department for Diagnostic Laboratory Medicine, Institute for Clinical Chemistry and Pathobiochemistry, University Hospital Tübingen, University of Tübingen, Tübingen, Germany.
  • Renström E; Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich, Tübingen, Germany.
  • Wollheim CB; German Center for Diabetes Research (DZD), Tübingen, Germany.
  • Engström G; Inserm U1283 / CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille; University of Lille, Lille University Hospital, Lille, France.
  • Weng J; Affinity Proteomics, Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden.
  • Pearson ER; Affinity Proteomics, Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden.
  • Franks PW; Department of Clinical Sciences, Lund University, Malmö, Sweden.
  • White MF; A.I. Virtanen Institute for Molecular Sciences, Department of Biotechnology and Molecular Medicine, University of Eastern Finland, Kuopio, Finland.
  • Duffin KL; Department of Clinical Sciences, Lund University, Malmö, Sweden.
  • Vaag AA; NIHR Exeter Clinical Research Facility, Royal Devon and Exeter Hospital and University of Exeter Medical School, Exeter, Devon, UK.
  • Laakso M; Division of Systems Medicine, University of Dundee, Ninewells Hospital & Medical School, Dundee, UK.
  • Stefan N; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
  • Groop L; Department of Clinical Sciences, Lund University, Malmö, Sweden.
  • De Marinis Y; Department of Clinical Sciences, Lund University, Malmö, Sweden.
Nat Commun ; 12(1): 6486, 2021 11 10.
Article em En | MEDLINE | ID: mdl-34759311

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Folistatina / Diabetes Mellitus Tipo 2 Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Folistatina / Diabetes Mellitus Tipo 2 Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article