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Conformational surveillance of Orai1 by a rhomboid intramembrane protease prevents inappropriate CRAC channel activation.
Grieve, Adam G; Yeh, Yi-Chun; Chang, Yu-Fen; Huang, Hsin-Yi; Zarcone, Lucrezia; Breuning, Johannes; Johnson, Nicholas; Strísovský, Kvido; Brown, Marion H; Parekh, Anant B; Freeman, Matthew.
Afiliação
  • Grieve AG; Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK. Electronic address: adam.grieve@bristol.ac.uk.
  • Yeh YC; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3PT, UK.
  • Chang YF; LumiSTAR Biotechnology, Inc., National Biotechnology Research Park, Taipei City 115, Taiwan.
  • Huang HY; LumiSTAR Biotechnology, Inc., National Biotechnology Research Park, Taipei City 115, Taiwan.
  • Zarcone L; Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK.
  • Breuning J; Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK.
  • Johnson N; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB), Prague, 166 10, Czech Republic.
  • Strísovský K; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB), Prague, 166 10, Czech Republic.
  • Brown MH; Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK.
  • Parekh AB; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3PT, UK.
  • Freeman M; Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK. Electronic address: matthew.freeman@path.ox.ac.uk.
Mol Cell ; 81(23): 4784-4798.e7, 2021 12 02.
Article em En | MEDLINE | ID: mdl-34800360
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeo Hidrolases / Serina Endopeptidases / Proteína ORAI1 Tipo de estudo: Prognostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeo Hidrolases / Serina Endopeptidases / Proteína ORAI1 Tipo de estudo: Prognostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article