Ultra-deep long-read sequencing detects IS-mediated gene duplications as a potential trigger to generate arrays of resistance genes and a mechanism to induce novel gene variants such as blaCTX-M-243.

Schuster, Christopher F; Weber, Robert E; Weig, Michael; Werner, Guido; Pfeifer, Yvonne

Schuster, Christopher F; Weber, Robert E; Weig, Michael; Werner, Guido; Pfeifer, Yvonne.

Afiliação

Schuster CF; Division of Nosocomial Pathogens and Antibiotic Resistance, Robert Koch Institute, Wernigerode, Germany.
Weber RE; Division of Nosocomial Pathogens and Antibiotic Resistance, Robert Koch Institute, Wernigerode, Germany.
Weig M; Institute for Medical Microbiology and Virology, University Medical Center Göttingen, Göttingen, Germany.
Werner G; Division of Nosocomial Pathogens and Antibiotic Resistance, Robert Koch Institute, Wernigerode, Germany.
Pfeifer Y; Division of Nosocomial Pathogens and Antibiotic Resistance, Robert Koch Institute, Wernigerode, Germany.

J Antimicrob Chemother ; 77(2): 381-390, 2022 02 02.

Article em En | MEDLINE | ID: mdl-34865035

Assuntos

Farmacorresistência Bacteriana/genética; Escherichia coli/genética; Duplicação Gênica; beta-Lactamases; Antibacterianos/farmacologia; Enterobacteriaceae/genética; Plasmídeos/genética; beta-Lactamases/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Beta-Lactamases / Duplicação Gênica / Farmacorresistência Bacteriana / Escherichia coli Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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