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Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance.
Gao, Yizhe; Felsky, Daniel; Reyes-Dumeyer, Dolly; Sariya, Sanjeev; Rentería, Miguel Arce; Ma, Yiyi; Klein, Hans-Ulrich; Cosentino, Stephanie; De Jager, Philip L; Bennett, David A; Brickman, Adam M; Schellenberg, Gerard D; Mayeux, Richard; Barral, Sandra.
Afiliação
  • Gao Y; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
  • Felsky D; Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
  • Reyes-Dumeyer D; Department of Psychiatry & Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.
  • Sariya S; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
  • Rentería MA; G.H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
  • Ma Y; Department of Neurology, Vagelos College of Physicians and Surgeons, New York-Presbyterian Hospital, Columbia University Medical Center, New York, New York, USA.
  • Klein HU; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
  • Cosentino S; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
  • De Jager PL; Department of Neurology, Vagelos College of Physicians and Surgeons, New York-Presbyterian Hospital, Columbia University Medical Center, New York, New York, USA.
  • Bennett DA; Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York, New York, USA.
  • Brickman AM; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
  • Schellenberg GD; Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York, New York, USA.
  • Mayeux R; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
  • Barral S; G.H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Alzheimers Dement ; 18(10): 1797-1811, 2022 10.
Article em En | MEDLINE | ID: mdl-34873813

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer / Memória Episódica Tipo de estudo: Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Aged / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer / Memória Episódica Tipo de estudo: Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Aged / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article