Capsid protein from red-spotted grouper nervous necrosis virus induces incomplete autophagy by inactivating the HSP90ab1-AKT-MTOR pathway.

Zhang, Wan-Wan; Jia, Peng; Lu, Xiao-Bing; Chen, Xiao-Qi; Weng, Jue-Hua; Jia, Kun-Tong; Yi, Mei-Sheng

Zhang, Wan-Wan; Jia, Peng; Lu, Xiao-Bing; Chen, Xiao-Qi; Weng, Jue-Hua; Jia, Kun-Tong; Yi, Mei-Sheng.

Afiliação

Zhang WW; School of Marine Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510000, China.
Jia P; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, Guangdong 519000, China.
Lu XB; Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, Guangzhou, Guangdong 510000, China.
Chen XQ; Pearl River Estuary Marine Ecosystem Research Station, Ministry of Education, Zhuhai, Guangdong 519000, China.
Weng JH; School of Marine Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510000, China.
Jia KT; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, Guangdong 519000, China.
Yi MS; Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, Guangzhou, Guangdong 510000, China.

Zool Res ; 43(1): 98-110, 2022 Jan 18.

Article em En | MEDLINE | ID: mdl-34904422

Assuntos

Bass; Proteínas do Capsídeo; Doenças dos Peixes; Nodaviridae; Infecções por Vírus de RNA; Animais; Autofagia; Proteínas do Capsídeo/fisiologia; Doenças dos Peixes/virologia; Proteínas de Peixes; Necrose/veterinária; Proteínas Proto-Oncogênicas c-akt; Infecções por Vírus de RNA/veterinária; Serina-Treonina Quinases TOR; Virulência

Palavras-chave

AKT-MTOR pathway; Autophagy; CP; HSP90ab1; NNV

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por Vírus de RNA / Bass / Nodaviridae / Proteínas do Capsídeo / Doenças dos Peixes Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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