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Design, synthesis, and evaluation of novel pyridone derivatives as potent BRD4 inhibitors for the potential treatment of prostate cancer.
Jiang, Wenhua; Wang, Xiaohui; Shu, Chengxia; Hou, Qiangqiang; Yang, Kexin; Wu, Xiaoxing.
Afiliação
  • Jiang W; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
  • Wang X; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
  • Shu C; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
  • Hou Q; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
  • Yang K; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
  • Wu X; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China. Electronic address: wu_xiaoxing@cpu.edu.cn.
Bioorg Chem ; 119: 105575, 2022 02.
Article em En | MEDLINE | ID: mdl-34995979
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Piridonas / Fatores de Transcrição / Desenho de Fármacos / Proteínas de Ciclo Celular / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Piridonas / Fatores de Transcrição / Desenho de Fármacos / Proteínas de Ciclo Celular / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article