The Heart and Cannabis (THC) Cohort: Differences in Baseline Health and Behaviors by Cannabis Use.
J Gen Intern Med
; 37(14): 3535-3544, 2022 11.
Article
em En
| MEDLINE
| ID: mdl-35013928
ABSTRACT
BACKGROUND:
Evidence on the cardiovascular health effects of cannabis use is limited. We designed a prospective cohort study of older Veterans (66 to 68 years) with coronary artery disease (CAD) to understand the cardiovascular consequences of cannabis use. We describe the cohort construction, baseline characteristics, and health behaviors that were associated with smoking cannabis.OBJECTIVE:
To understand the cardiovascular consequences of cannabis use.DESIGN:
We designed a prospective cohort study of older Veterans (66 to 68 years) with CAD.PARTICIPANTS:
A total of 1,015 current cannabis smokers and 3,270 non-cannabis smokers with CAD. MAINMEASURES:
Using logistic regression, we examined the association of baseline variables with smoking cannabis in the past 30 days.RESULTS:
The current cannabis smokers and non-current smokers were predominantly male (97.2% vs 97.1%, p=0.96). Characteristics associated with recent cannabis use in multivariable analyses included lack of a high school education (odds ratio [OR] 2.15, 95% confidence interval [CI] 1.10 to 4.19), financial difficulty (OR 1.47, 95% CI 1.02 to 2.11), tobacco use (OR 3.02, 95% CI 1.66 to 5.48), current drug use (OR 2.82, 95% CI 1.06 to 7.46), and prior drug use (OR 2.84, 95% CI 2.11 to 3.82). In contrast, compared to individuals with 0 to 1 comorbid conditions, those with 5 chronic conditions or more (OR 0.43, 95% CI 0.27 to 0.70) were less likely to smoke cannabis.CONCLUSIONS:
In this older high-risk cohort, smoking cannabis was associated with higher social and behavioral risk, but with fewer chronic health conditions.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Cannabis
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Fumar Maconha
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article