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Expression of the transcription factor PU.1 induces the generation of microglia-like cells in human cortical organoids.
Cakir, Bilal; Tanaka, Yoshiaki; Kiral, Ferdi Ridvan; Xiang, Yangfei; Dagliyan, Onur; Wang, Juan; Lee, Maria; Greaney, Allison M; Yang, Woo Sub; duBoulay, Catherine; Kural, Mehmet Hamdi; Patterson, Benjamin; Zhong, Mei; Kim, Jonghun; Bai, Yalai; Min, Wang; Niklason, Laura E; Patra, Prabir; Park, In-Hyun.
Afiliação
  • Cakir B; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.
  • Tanaka Y; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.
  • Kiral FR; Department of Medicine, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec, H1T 2M4, Canada.
  • Xiang Y; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.
  • Dagliyan O; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.
  • Wang J; Department of Neurobiology, Harvard Medical School, Boston, MA, 02115, USA.
  • Lee M; Department of Anesthesiology, Yale School of Medicine, New Haven, CT, 06520, USA.
  • Greaney AM; Department of Molecular, Cellular, Developmental Biology, Yale University, New Haven, CT, 06520, USA.
  • Yang WS; Department of Biomedical Engineering, Yale University, New Haven, CT, 06520, USA.
  • duBoulay C; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.
  • Kural MH; Department of Biology, Colby College, Waterville, ME, 06901, USA.
  • Patterson B; Department of Anesthesiology, Yale School of Medicine, New Haven, CT, 06520, USA.
  • Zhong M; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.
  • Kim J; Department of Cell Biology, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.
  • Bai Y; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.
  • Min W; Department of Pathology, Yale School of Medicine, New Haven, CT, 06520, USA.
  • Niklason LE; Interdepartmental Program in Vascular Biology and Therapeutics, Department of Pathology, Yale School of Medicine, New Haven, CT, 06520, USA.
  • Patra P; Department of Anesthesiology, Yale School of Medicine, New Haven, CT, 06520, USA.
  • Park IH; Department of Biomedical Engineering, Yale University, New Haven, CT, 06520, USA.
Nat Commun ; 13(1): 430, 2022 01 20.
Article em En | MEDLINE | ID: mdl-35058453
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Organoides / Transativadores / Córtex Cerebral / Proteínas Proto-Oncogênicas / Microglia Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Organoides / Transativadores / Córtex Cerebral / Proteínas Proto-Oncogênicas / Microglia Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article