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Lysosomal cystine mobilization shapes the response of TORC1 and tissue growth to fasting.
Jouandin, Patrick; Marelja, Zvonimir; Shih, Yung-Hsin; Parkhitko, Andrey A; Dambowsky, Miriam; Asara, John M; Nemazanyy, Ivan; Dibble, Christian C; Simons, Matias; Perrimon, Norbert.
Afiliação
  • Jouandin P; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Marelja Z; Université de Paris, INSERM, IHU Imagine - Institut des maladies génétiques, Laboratory of Epithelial Biology and Disease, 75015 Paris, France.
  • Shih YH; Institute of Human Genetics, University Hospital Heidelberg, 69120 Heidelberg, Germany.
  • Parkhitko AA; Institute of Human Genetics, University Hospital Heidelberg, 69120 Heidelberg, Germany.
  • Dambowsky M; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Asara JM; Université de Paris, INSERM, IHU Imagine - Institut des maladies génétiques, Laboratory of Epithelial Biology and Disease, 75015 Paris, France.
  • Nemazanyy I; Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
  • Dibble CC; Department of Medicine, Harvard Medical School, Boston, MA 02175, USA.
  • Simons M; Platform for Metabolic Analyses, Structure Fédérative de Recherche Necker, INSERM US24/CNRS UMS 3633, Paris 75015, France.
  • Perrimon N; Department of Pathology and Cancer Center, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
Science ; 375(6582): eabc4203, 2022 02 18.
Article em En | MEDLINE | ID: mdl-35175796
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Jejum / Cistina / Proteínas de Drosophila / Drosophila melanogaster / Alvo Mecanístico do Complexo 1 de Rapamicina / Lisossomos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Jejum / Cistina / Proteínas de Drosophila / Drosophila melanogaster / Alvo Mecanístico do Complexo 1 de Rapamicina / Lisossomos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article