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Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation.
Zhang, Chuanchao; Zhou, Bo; Gu, Feng; Liu, Hongmei; Wu, Honglin; Yao, Fuwen; Zheng, Hui; Fu, Hui; Chong, Wei; Cai, Shurui; Huang, Min; Ma, Xiaolu; Guo, Zhifang; Li, Tingting; Deng, Wenyuan; Zheng, Meiwen; Ji, Qiao; Zhao, Yongliang; Ma, Yongjie; Wang, Qi-En; Tang, Tie-Shan; Guo, Caixia.
Afiliação
  • Zhang C; CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China.
  • Zhou B; CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China. Electronic address: zhoub@big.ac.cn.
  • Gu F; Department of Breast Cancer Pathology and Research Laboratory, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.
  • Liu H; State Key Laboratory of Membrane Biology, Institute of Zoology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100101, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China.
  • Wu H; CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China; State Key Laboratory of Membrane Biology, Institute of Zoology, University of
  • Yao F; CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China.
  • Zheng H; CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China.
  • Fu H; CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China.
  • Chong W; Department of Breast Cancer Pathology and Research Laboratory, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.
  • Cai S; Department of Radiation Oncology, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43016, USA.
  • Huang M; CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China.
  • Ma X; CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China.
  • Guo Z; Department of Breast Cancer Pathology and Research Laboratory, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.
  • Li T; State Key Laboratory of Membrane Biology, Institute of Zoology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100101, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China.
  • Deng W; CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China.
  • Zheng M; CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China.
  • Ji Q; CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China.
  • Zhao Y; CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China.
  • Ma Y; Department of Breast Cancer Pathology and Research Laboratory, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.
  • Wang QE; Department of Radiation Oncology, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43016, USA.
  • Tang TS; State Key Laboratory of Membrane Biology, Institute of Zoology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100101, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China; Beijing Institute for Stem Cell and Regenerativ
  • Guo C; CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China. Electronic address: guocx@big.ac.cn.
Mol Cell ; 82(7): 1297-1312.e8, 2022 04 07.
Article em En | MEDLINE | ID: mdl-35219381
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Endodesoxirribonucleases / RNA Longo não Codificante / Poli ADP Ribosilação / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Endodesoxirribonucleases / RNA Longo não Codificante / Poli ADP Ribosilação / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article