GAS6-mediated dialogue between decidual stromal cells and macrophages is essential for early pregnancy maintenance by inducing M2-like polarization and cell proliferation of decidual macrophages.

Dai, Jing-Cong; Yang, Jia-Yan; Chang, Rui-Qi; Liang, Yan; Hu, Xiao-Yu; Li, Hu; You, Shuang; He, Fan; Hu, Li-Na

Dai, Jing-Cong; Yang, Jia-Yan; Chang, Rui-Qi; Liang, Yan; Hu, Xiao-Yu; Li, Hu; You, Shuang; He, Fan; Hu, Li-Na.

Afiliação

Dai JC; Obstetrics and Gynecology Department, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yang JY; Obstetrics and Gynecology Department, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chang RQ; The Center for Reproductive Medicine, Obstetrics and Gynecology Department, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Liang Y; Joint International Research Lab for Reproduction and Development, Ministry of Education, Chongqing, China.
Hu XY; Obstetrics and Gynecology Department, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Li H; Obstetrics and Gynecology Department, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
You S; Obstetrics and Gynecology Department, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
He F; Obstetrics and Gynecology Department, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Hu LN; The Center for Reproductive Medicine, Obstetrics and Gynecology Department, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Mol Hum Reprod ; 28(3)2022 03 08.

Article em En | MEDLINE | ID: mdl-35258594

Assuntos

Aborto Espontâneo; Decídua; Peptídeos e Proteínas de Sinalização Intercelular/metabolismo; Aborto Espontâneo/metabolismo; Proliferação de Células; Decídua/metabolismo; Feminino; Humanos; Peptídeos e Proteínas de Sinalização Intercelular/genética; Peptídeos e Proteínas de Sinalização Intercelular/farmacologia; Macrófagos/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Gravidez; Manutenção da Gravidez; Células Estromais/metabolismo; c-Mer Tirosina Quinase/genética; c-Mer Tirosina Quinase/metabolismo

Palavras-chave

CD163; M2-like polarization; cell proliferation; decidual macrophages; decidual stromal cells; growth arrest-specific factor 6; maternalfoetal interface; miscarriage; pregnancy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aborto Espontâneo / Decídua / Peptídeos e Proteínas de Sinalização Intercelular Limite: Female / Humans / Pregnancy Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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