[A favorable clinical course of acute myeloid leukemia with t (6;21;8)(p23;q22;q22)].
Rinsho Ketsueki
; 63(2): 104-107, 2022.
Article
em Ja
| MEDLINE
| ID: mdl-35264498
ABSTRACT
Variants of the t (8;21) (q22;q22) involving chromosome 8, 21, and other chromosomes account for about 3% of all t (8;21) (q22;q22) in patients with acute myeloid leukemia (AML). However, the prognosis of AML with variant t (8;21) remains unknown due to the scarcity of reported cases. Herein we report a case of AML with t (6;21;8) (p23;q22;q22). Fluorescence in situ hybridization confirmed a RUNX1-RUNX1T1 fusion signal on the derivative chromosome 8. This is the first report on a variant of t (8;21) involving the breakpoint 6p23. After induction chemotherapy, our patient achieved complete remission and has been stable for four years.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Cromossomos Humanos Par 8
/
Leucemia Mieloide Aguda
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
Ja
Ano de publicação:
2022
Tipo de documento:
Article