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Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models.
Prieto Huarcaya, Susy; Drobny, Alice; Marques, André R A; Di Spiezio, Alessandro; Dobert, Jan Philipp; Balta, Denise; Werner, Christian; Rizo, Tania; Gallwitz, Lisa; Bub, Simon; Stojkovska, Iva; Belur, Nandkishore R; Fogh, Jens; Mazzulli, Joseph R; Xiang, Wei; Fulzele, Amitkumar; Dejung, Mario; Sauer, Markus; Winner, Beate; Rose-John, Stefan; Arnold, Philipp; Saftig, Paul; Zunke, Friederike.
Afiliação
  • Prieto Huarcaya S; Institute of Biochemistry, Christian-Albrechts-University Kiel, Kiel, Germany.
  • Drobny A; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (Fau), Erlangen, Germany.
  • Marques ARA; iNOVA4Health, Chronic Diseases Research Center (CEDOC), Nova Medical School, Nms, Nova University Lisbon, Lisboa, Portugal.
  • Di Spiezio A; Institute of Biochemistry, Christian-Albrechts-University Kiel, Kiel, Germany.
  • Dobert JP; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (Fau), Erlangen, Germany.
  • Balta D; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (Fau), Erlangen, Germany.
  • Werner C; Department of Biotechnology and Biophysics, University of Würzburg, Biocenter, Am Hubland, Würzburg, Germany.
  • Rizo T; Department of Stem Cell Biology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
  • Gallwitz L; Institute of Biochemistry, Christian-Albrechts-University Kiel, Kiel, Germany.
  • Bub S; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (Fau), Erlangen, Germany.
  • Stojkovska I; The Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois USA.
  • Belur NR; The Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois USA.
  • Fogh J; OrfoNeuro ApS, Lynge, Denmark.
  • Mazzulli JR; Department of Biotechnology and Biophysics, University of Würzburg, Biocenter, Am Hubland, Würzburg, Germany.
  • Xiang W; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (Fau), Erlangen, Germany.
  • Fulzele A; Institute of Molecular Biology (IMB), Ackermannweg 4, Mainz, Germany.
  • Dejung M; Institute of Molecular Biology (IMB), Ackermannweg 4, Mainz, Germany.
  • Sauer M; Department of Biotechnology and Biophysics, University of Würzburg, Biocenter, Am Hubland, Würzburg, Germany.
  • Winner B; Department of Stem Cell Biology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
  • Rose-John S; Institute of Biochemistry, Christian-Albrechts-University Kiel, Kiel, Germany.
  • Arnold P; Institute of Functional and Clinical Anatomy, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Germany.
  • Saftig P; Institute of Biochemistry, Christian-Albrechts-University Kiel, Kiel, Germany.
  • Zunke F; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (Fau), Erlangen, Germany.
Autophagy ; 18(5): 1127-1151, 2022 05.
Article em En | MEDLINE | ID: mdl-35287553
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Sinucleinopatias / Lipofuscinoses Ceroides Neuronais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Sinucleinopatias / Lipofuscinoses Ceroides Neuronais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article