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Characterization of patients with occupational allergy to two new epoxy hardener compounds.
Suomela, Sari; Pesonen, Maria; Ylinen, Katriina; Aalto-Korte, Kristiina; Suuronen, Katri.
Afiliação
  • Suomela S; Occupational Medicine, Finnish Institute of Occupational Health (FIOH), Helsinki, Finland.
  • Pesonen M; Occupational Medicine, Finnish Institute of Occupational Health (FIOH), Helsinki, Finland.
  • Ylinen K; Work Environment Laboratories, Finnish Institute of Occupational Health (FIOH), Helsinki, Finland.
  • Aalto-Korte K; Occupational Medicine, Finnish Institute of Occupational Health (FIOH), Helsinki, Finland.
  • Suuronen K; Occupational Medicine, Finnish Institute of Occupational Health (FIOH), Helsinki, Finland.
Contact Dermatitis ; 87(1): 81-88, 2022 Jul.
Article em En | MEDLINE | ID: mdl-35293005
ABSTRACT

BACKGROUND:

The practical importance of two recently described epoxy hardener allergens-1,3-benzenedimethanamine, N-(2-phenylethyl) derivatives (1,3-BDMA-D) and hydrogenated formaldehyde benzenamine polymer (FBAP)-as occupational allergens remains to be defined.

OBJECTIVES:

To describe patients diagnosed at the Finnish Institute of Occupational Health (FIOH) with positive reactions to 1,3-BDMA-D or FBAP.

METHODS:

We searched FIOH's patch-test files from January 2017 to December 2020 for patients examined due to suspected occupational contact allergy to epoxy compounds. We analyzed the patch-test results and sources of exposure to various epoxy hardeners and focused on occupations, symptoms, and the sources of exposure to 1,3-BDMA-D and FBAP.

RESULTS:

During the study period, 102 patients were examined at FIOH for suspected occupational contact allergy to epoxy compounds. Of these, 19 (19%) were diagnosed with contact allergy to 1,3-BDMA-D (n = 10) or FBAP (n = 12). The largest occupational group was sewage pipe reliners (n = 8). Seven different hardener products contained FBAP, whereas 1,3-BDMA-D was present in only one hardener used by spray painters.

CONCLUSIONS:

A substantial number of patients with suspected occupational epoxy resin system allergy tested positive to in-house test substances of 1,3-BDMA-D and/or FBAP.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dermatite Alérgica de Contato / Dermatite Ocupacional Tipo de estudo: Diagnostic_studies / Etiology_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dermatite Alérgica de Contato / Dermatite Ocupacional Tipo de estudo: Diagnostic_studies / Etiology_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article