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Characterization of hypervirulent Klebsiella pneumoniae isolates in Belgium.
Anantharajah, Ahalieyah; Deltombe, Matthieu; de Barsy, Marie; Evrard, Stephanie; Denis, Olivier; Bogaerts, Pierre; Hallin, Marie; Miendje Deyi, Véronique Yvette; Pierard, Denis; Bruynseels, Peggy; Boelens, Jerina; Glupczynski, Youri; Huang, Te-Din.
Afiliação
  • Anantharajah A; Department of Clinical Microbiology, National Reference Center for Antibiotic-Resistant Gram-Negative Bacilli, CHU UCL Namur, Yvoir, Belgium. ahalieyah.anantharajah@saintluc.uclouvain.be.
  • Deltombe M; Department of Clinical Microbiology, Cliniques Universitaires Saint-Luc, UCL, Brussels, Belgium. ahalieyah.anantharajah@saintluc.uclouvain.be.
  • de Barsy M; Department of Clinical Microbiology, National Reference Center for Antibiotic-Resistant Gram-Negative Bacilli, CHU UCL Namur, Yvoir, Belgium.
  • Evrard S; Department of Clinical Microbiology, National Reference Center for Antibiotic-Resistant Gram-Negative Bacilli, CHU UCL Namur, Yvoir, Belgium.
  • Denis O; Department of Clinical Microbiology, National Reference Center for Antibiotic-Resistant Gram-Negative Bacilli, CHU UCL Namur, Yvoir, Belgium.
  • Bogaerts P; Department of Clinical Microbiology, National Reference Center for Antibiotic-Resistant Gram-Negative Bacilli, CHU UCL Namur, Yvoir, Belgium.
  • Hallin M; Department of Clinical Microbiology, National Reference Center for Antibiotic-Resistant Gram-Negative Bacilli, CHU UCL Namur, Yvoir, Belgium.
  • Miendje Deyi VY; Department of Microbiology, Laboratoire Hospitalier Universitaire de Bruxelles (LHUB-ULB), Brussels, Belgium.
  • Pierard D; Department of Microbiology, Laboratoire Hospitalier Universitaire de Bruxelles (LHUB-ULB), Brussels, Belgium.
  • Bruynseels P; Department of Microbiology, Universiteit Ziekenhuis Brussel, Brussels, Belgium.
  • Boelens J; Department of Microbiology, Ziekenhuis Netwerk Antwerpen, Antwerp, Belgium.
  • Glupczynski Y; Department of Microbiology, Ghent University Hospital, Ghent, Belgium.
  • Huang TD; Department of Clinical Microbiology, National Reference Center for Antibiotic-Resistant Gram-Negative Bacilli, CHU UCL Namur, Yvoir, Belgium.
Eur J Clin Microbiol Infect Dis ; 41(5): 859-865, 2022 May.
Article em En | MEDLINE | ID: mdl-35353281
ABSTRACT
Hypervirulent Klebsiella pneumoniae (hvKp) raised concern worldwide. We studied 22 hvKp clinical invasive isolates referred to the Belgian national reference laboratory between 2014 and 2020. Sixty-four percent of the isolates expressed K2 capsular serotype and belonged to 7 different MLST lineages, while 32% expressed K1 (all belonging to ST23) and were associated with liver abscesses. Primary extra-hepatic infections were reported in 36% and sepsis for 95% of the patients with 30% of deaths. Improved clinical and microbiological diagnostics are required as hvKp may represent an underestimated cause of community-acquired invasive infections in Belgium.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por Klebsiella / Infecções Comunitárias Adquiridas Limite: Humans País/Região como assunto: Europa Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por Klebsiella / Infecções Comunitárias Adquiridas Limite: Humans País/Região como assunto: Europa Idioma: En Ano de publicação: 2022 Tipo de documento: Article