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Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential.
Nakao, Tetsushi; Bick, Alexander G; Taub, Margaret A; Zekavat, Seyedeh M; Uddin, Md M; Niroula, Abhishek; Carty, Cara L; Lane, John; Honigberg, Michael C; Weinstock, Joshua S; Pampana, Akhil; Gibson, Christopher J; Griffin, Gabriel K; Clarke, Shoa L; Bhattacharya, Romit; Assimes, Themistocles L; Emery, Leslie S; Stilp, Adrienne M; Wong, Quenna; Broome, Jai; Laurie, Cecelia A; Khan, Alyna T; Smith, Albert V; Blackwell, Thomas W; Codd, Veryan; Nelson, Christopher P; Yoneda, Zachary T; Peralta, Juan M; Bowden, Donald W; Irvin, Marguerite R; Boorgula, Meher; Zhao, Wei; Yanek, Lisa R; Wiggins, Kerri L; Hixson, James E; Gu, C Charles; Peloso, Gina M; Roden, Dan M; Reupena, Muagututi'a S; Hwu, Chii-Min; DeMeo, Dawn L; North, Kari E; Kelly, Shannon; Musani, Solomon K; Bis, Joshua C; Lloyd-Jones, Donald M; Johnsen, Jill M; Preuss, Michael; Tracy, Russell P; Peyser, Patricia A.
Afiliação
  • Nakao T; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Bick AG; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
  • Taub MA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Zekavat SM; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Uddin MM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Niroula A; Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, TN, USA.
  • Carty CL; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Lane J; Yale University School of Medicine, New Haven, CT, USA.
  • Honigberg MC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Weinstock JS; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
  • Pampana A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Gibson CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Griffin GK; Department of Laboratory Medicine, Lund University, Lund, Sweden.
  • Clarke SL; Initiative for Research and Education to Advance Community Health, Washington State University, Seattle, WA, USA.
  • Bhattacharya R; Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN, USA.
  • Assimes TL; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Emery LS; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
  • Stilp AM; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Wong Q; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Broome J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Laurie CA; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
  • Khan AT; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Smith AV; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Blackwell TW; Department of Pathology, Harvard Medical School, Boston, MA, USA.
  • Codd V; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.
  • Nelson CP; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
  • Yoneda ZT; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
  • Peralta JM; Division of Cardiology, Massachusetts General Hospital, Boston, MA, USA.
  • Bowden DW; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
  • Irvin MR; VA Palo Alto Health Care System, Palo Alto, CA, USA.
  • Boorgula M; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Zhao W; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Yanek LR; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Wiggins KL; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Hixson JE; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Gu CC; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Peloso GM; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Roden DM; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Reupena MS; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.
  • Hwu CM; National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
  • DeMeo DL; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.
  • North KE; National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
  • Kelly S; Division of Cardiology, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Musani SK; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.
  • Bis JC; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.
  • Lloyd-Jones DM; Department of Biostatistics, School of Public Health, University of Alabama, Birmingham, AL, USA.
  • Johnsen JM; Division of Biomedical Informatics and Personalized Medicine and the Colorado Center for Personalized Medicine, School of Medicine, University of Colorado, Aurora, CO, USA.
  • Preuss M; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
  • Tracy RP; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Peyser PA; Department of Medicine, University of Washington, Seattle, WA, USA.
Sci Adv ; 8(14): eabl6579, 2022 Apr 08.
Article em En | MEDLINE | ID: mdl-35385311
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Etiology_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Etiology_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article