Myeloid Cell PKM2 Deletion Enhances Efferocytosis and Reduces Atherosclerosis.

Doddapattar, Prakash; Dev, Rishabh; Ghatge, Madankumar; Patel, Rakesh B; Jain, Manish; Dhanesha, Nirav; Lentz, Steven R; Chauhan, Anil K

Doddapattar, Prakash; Dev, Rishabh; Ghatge, Madankumar; Patel, Rakesh B; Jain, Manish; Dhanesha, Nirav; Lentz, Steven R; Chauhan, Anil K.

Afiliação

Doddapattar P; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa.
Dev R; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa.
Ghatge M; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa.
Patel RB; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa.
Jain M; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa.
Dhanesha N; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa.
Lentz SR; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa.
Chauhan AK; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa.

Circ Res ; 130(9): 1289-1305, 2022 04 29.

Article em En | MEDLINE | ID: mdl-35400205

Assuntos

Aterosclerose; Piruvato Quinase/metabolismo; Receptores de LDL; Animais; Aorta/metabolismo; Aterosclerose/genética; Aterosclerose/metabolismo; Aterosclerose/prevenção & controle; Feminino; Macrófagos/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Células Mieloides/metabolismo; Fagocitose; Receptores de LDL/metabolismo

Palavras-chave

atherosclerosis; gene expression; inflammation; macrophages; pyruvate kinase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piruvato Quinase / Receptores de LDL / Aterosclerose Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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