Noninvasive Evaluation of Multidrug Resistance via Imaging of ABCG2/BCRP Multidrug Transporter in Lung Cancer Xenograft Models.

Li, Cuicui; Yang, Qi; Chen, Zhao; Qiu, Yongkang; Du, Yujing; Wang, Rongfu; He, Qihua; Yang, Jigang; Zhen, Hongying; Kang, Lei

Li, Cuicui; Yang, Qi; Chen, Zhao; Qiu, Yongkang; Du, Yujing; Wang, Rongfu; He, Qihua; Yang, Jigang; Zhen, Hongying; Kang, Lei.

Afiliação

Li C; Department of Nuclear Medicine, Capital Medical University Affiliated Beijing Friendship Hospital, Beijing 100050, China.
Yang Q; Department of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China.
Chen Z; Department of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China.
Qiu Y; Department of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China.
Du Y; Department of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China.
Wang R; Department of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China.
He Q; Department of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China.
Yang J; Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Zhen H; Department of Nuclear Medicine, Capital Medical University Affiliated Beijing Friendship Hospital, Beijing 100050, China.
Kang L; Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.

Mol Pharm ; 19(10): 3521-3529, 2022 10 03.

Article em En | MEDLINE | ID: mdl-35427142

Assuntos

Neoplasias Pulmonares; Mitoxantrona; Membro 2 da Subfamília G de Transportadores de Cassetes de Ligação de ATP/metabolismo; Trifosfato de Adenosina/metabolismo; Animais; Anticorpos Monoclonais/metabolismo; Carbocianinas; Linhagem Celular Tumoral; Desferroxamina; Modelos Animais de Doenças; Resistência a Múltiplos Medicamentos; Resistencia a Medicamentos Antineoplásicos; Xenoenxertos; Humanos; Neoplasias Pulmonares/tratamento farmacológico; Camundongos; Proteínas de Neoplasias/metabolismo; Distribuição Tecidual

Palavras-chave

ABCG2; MDR; fluorescent imaging; immunoPET; lung cancer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mitoxantrona / Neoplasias Pulmonares Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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