Human placental mesenchymal stem cell derived exosomes exhibit anti-inflammatory effects via TLR4-mediated NF-&#954;B/MAPK and PI3K signaling pathways.

Hu, Yiwei; Qu, Huiting; He, Jie; Zhong, Hongyao; He, Shoukai; Zhao, Peng; Zhang, Leyao; Chen, Jinghua; Deng, Chao

Human placental mesenchymal stem cell derived exosomes exhibit anti-inflammatory effects via TLR4-mediated NF-κB/MAPK and PI3K signaling pathways.

Hu, Yiwei; Qu, Huiting; He, Jie; Zhong, Hongyao; He, Shoukai; Zhao, Peng; Zhang, Leyao; Chen, Jinghua; Deng, Chao.

Afiliação

Hu Y; Wuxi School of Medicine, Jiangnan University, Wuxi, China.
Qu H; Wuxi School of Medicine, Jiangnan University, Wuxi, China.
He J; Wuxi School of Medicine, Jiangnan University, Wuxi, China.
Zhong H; Wuxi School of Medicine, Jiangnan University, Wuxi, China.
He S; Wuxi School of Medicine, Jiangnan University, Wuxi, China.
Zhao P; Affiliated Hospital of Jiangnan University, Wuxi, China.
Zhang L; The Ninth People's Hospital of Wuxi, China.
Chen J; School of Pharmaceutics Science, Jiangnan University, Wuxi, China.
Deng C; Wuxi School of Medicine, Jiangnan University, Wuxi, China;, Email: dcao@jiangnan.edu.cn.

Pharmazie ; 77(3): 112-117, 2022 04 10.

Article em En | MEDLINE | ID: mdl-35459439

Assuntos

Exossomos; Células-Tronco Mesenquimais; Receptor 4 Toll-Like; Anti-Inflamatórios/farmacologia; Exossomos/metabolismo; Feminino; Humanos; Inflamação/metabolismo; NF-kappa B/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Placenta/metabolismo; Gravidez; Transdução de Sinais; Receptor 4 Toll-Like/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor 4 Toll-Like / Exossomos / Células-Tronco Mesenquimais Limite: Female / Humans / Pregnancy Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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