Single cell variability of CRISPR-Cas interference and adaptation.

McKenzie, Rebecca E; Keizer, Emma M; Vink, Jochem N A; van Lopik, Jasper; Büke, Ferhat; Kalkman, Vera; Fleck, Christian; Tans, Sander J; Brouns, Stan J J

McKenzie, Rebecca E; Keizer, Emma M; Vink, Jochem N A; van Lopik, Jasper; Büke, Ferhat; Kalkman, Vera; Fleck, Christian; Tans, Sander J; Brouns, Stan J J.

Afiliação

McKenzie RE; Department of Bionanoscience, Delft University of Technology, Delft, The Netherlands.
Keizer EM; Kavli Institute of Nanoscience, Delft, The Netherlands.
Vink JNA; AMOLF, Amsterdam, The Netherlands.
van Lopik J; Biometris, Department of Mathematical and Statistical Methods, Wageningen University, Wageningen, The Netherlands.
Büke F; Department of Bionanoscience, Delft University of Technology, Delft, The Netherlands.
Kalkman V; Kavli Institute of Nanoscience, Delft, The Netherlands.
Fleck C; Department of Bionanoscience, Delft University of Technology, Delft, The Netherlands.
Tans SJ; Kavli Institute of Nanoscience, Delft, The Netherlands.
Brouns SJJ; Department of Bionanoscience, Delft University of Technology, Delft, The Netherlands.

Mol Syst Biol ; 18(4): e10680, 2022 04.

Article em En | MEDLINE | ID: mdl-35467080

Assuntos

Bacteriófagos; Sistemas CRISPR-Cas; Adaptação Fisiológica/genética; Sistemas CRISPR-Cas/genética; DNA/metabolismo; Escherichia coli/genética; Escherichia coli/metabolismo

Palavras-chave

agent-based simulations; single-cell analysis; spacer acquisition; time-lapse microscopy; type I CRISPR-Cas

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bacteriófagos / Sistemas CRISPR-Cas Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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