Y-Chromosome Gene, <i>Uty</i>, Protects Against Pulmonary Hypertension by Reducing Proinflammatory Chemokines.

Cunningham, Christine M; Li, Min; Ruffenach, Gregoire; Doshi, Mitali; Aryan, Laila; Hong, Jason; Park, John; Hrncir, Haley; Medzikovic, Lejla; Umar, Soban; Arnold, Arthur P; Eghbali, Mansoureh

Y-Chromosome Gene, Uty, Protects Against Pulmonary Hypertension by Reducing Proinflammatory Chemokines.

Cunningham, Christine M; Li, Min; Ruffenach, Gregoire; Doshi, Mitali; Aryan, Laila; Hong, Jason; Park, John; Hrncir, Haley; Medzikovic, Lejla; Umar, Soban; Arnold, Arthur P; Eghbali, Mansoureh.

Afiliação

Cunningham CM; Division of Molecular Medicine, Department of Anesthesiology.
Li M; School of Medicine, Stanford University, Stanford, California.
Ruffenach G; VA Palo Alto Health Care System, Palo Alto, California; and.
Doshi M; Division of Molecular Medicine, Department of Anesthesiology.
Aryan L; Division of Molecular Medicine, Department of Anesthesiology.
Hong J; Division of Molecular Medicine, Department of Anesthesiology.
Park J; University of Massachusetts Medical School, Worcester, Massachusetts.
Hrncir H; Division of Molecular Medicine, Department of Anesthesiology.
Medzikovic L; Division of Molecular Medicine, Department of Anesthesiology.
Umar S; Division of Pulmonary and Critical Care Medicine, Department of Medicine, and.
Arnold AP; Division of Molecular Medicine, Department of Anesthesiology.
Eghbali M; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, California.

Am J Respir Crit Care Med ; 206(2): 186-196, 2022 07 15.

Article em En | MEDLINE | ID: mdl-35504005

Assuntos

Quimiocinas; Hipertensão Pulmonar; Antígenos de Histocompatibilidade Menor; Proteínas Nucleares; Animais; Quimiocinas/metabolismo; Modelos Animais de Doenças; Células Endoteliais/metabolismo; Hipertensão Pulmonar Primária Familiar/genética; Feminino; Genes Ligados ao Cromossomo Y; Humanos; Hipertensão Pulmonar/genética; Hipóxia; Masculino; Camundongos; Antígenos de Histocompatibilidade Menor/genética; Proteínas Nucleares/genética; Artéria Pulmonar; Ratos

Palavras-chave

CXCL10; CXCL9; endothelial cells; pulmonary arterial hypertension; sex differences

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Antígenos de Histocompatibilidade Menor / Quimiocinas / Hipertensão Pulmonar Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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