Presenilin enhancer 2 is crucial for the transition of apical progenitors into neurons but into not basal progenitors in the developing hippocampus.

Xia, Yingqian; Zhang, Yizhi; Xu, Min; Zou, Xiaochuan; Gao, Jun; Ji, Mu-Huo; Chen, Guiquan

Xia, Yingqian; Zhang, Yizhi; Xu, Min; Zou, Xiaochuan; Gao, Jun; Ji, Mu-Huo; Chen, Guiquan.

Afiliação

Xia Y; Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, 12 Xuefu Avenue, Nanjing, Jiangsu, China, 210061.
Zhang Y; Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, 12 Xuefu Avenue, Nanjing, Jiangsu, China, 210061.
Xu M; Department of Neurobiology, Key Laboratory of Human Functional Genomics of Jiangsu, Nanjing Medical University, Nanjing, Jiangsu, China, 211166.
Zou X; Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, 12 Xuefu Avenue, Nanjing, Jiangsu, China, 210061.
Gao J; Department of Neurobiology, Key Laboratory of Human Functional Genomics of Jiangsu, Nanjing Medical University, Nanjing, Jiangsu, China, 211166.
Ji MH; Department of Anesthesiology, The Second Affiliated Hospital, Nanjing Medical University, Nanjing, China, 210003.
Chen G; Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, 12 Xuefu Avenue, Nanjing, Jiangsu, China, 210061.

Development ; 149(10)2022 05 15.

Article em En | MEDLINE | ID: mdl-35575074

Assuntos

Hipocampo; Neurônios; Animais; Hipocampo/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Neurogênese/genética; Neurônios/metabolismo; Presenilinas/metabolismo

Palavras-chave

Apical progenitor; Basal progenitor; Hippocampus; Immature neuron; Pen2 (Psenen)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hipocampo / Neurônios Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hipocampo / Neurônios Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article